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Symbol
Name
ID

Rps6ka3
ribosomal protein S6 kinase polypeptide 3
MGI:104557

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Ventriculomegaly	Delayed speech and language development	Intellectual disability	Intellectual disability, mild	Global developmental delay	Motor delay	Seizure
Disease(s) Associated with RPS6KA3	Microcephaly	Ventriculomegaly	Delayed speech and language development	Intellectual disability	Intellectual disability, mild	Global developmental delay	Motor delay	Seizure
Coffin-Lowry syndrome
non-syndromic X-linked intellectual disability 19

Mouse Phenotypes		nervous system phenotype	abnormal dendritic spine morphology	abnormal synapse morphology	abnormal postsynaptic density morphology	abnormal CNS synaptic transmission	short excitatory postsynaptic current decay time	abnormal excitatory postsynaptic potential	reduced AMPA-mediated synaptic currents
Availability	Mouse Genotype	nervous system phenotype	abnormal dendritic spine morphology	abnormal synapse morphology	abnormal postsynaptic density morphology	abnormal CNS synaptic transmission	short excitatory postsynaptic current decay time	abnormal excitatory postsynaptic potential	reduced AMPA-mediated synaptic currents
	Rps6ka3^tm1.1Kry/Rps6ka3^tm1.1Kry	*
	Rps6ka3^tm1.1Kry/Rps6ka3⁺	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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